abstract：:Myristic acid, the 14-carbon saturated fatty acid (C14:0), is associated to an increased cardiovascular disease risk. Since it is found in low concentration in cells, its specific properties have not been fully analyzed. The aim of this study was to explore the cell response to this fatty acid to help explaining clini...

journal_title：Journal of proteomics

authors： Speziali G,Liesinger L,Gindlhuber J,Leopold C,Pucher B,Brandi J,Castagna A,Tomin T,Krenn P,Thallinger GG,Olivieri O,Martinelli N,Kratky D,Schittmayer M,Birner-Gruenberger R,Cecconi D

更新日期：2018-06-15 00:00:00

abstract：:Flooding negatively affects the growth of soybean, whereas the plant-derived smoke enhances seedling growth of crops. To clarify the mechanism underlying the recovery from flooding stress, proteomic analysis was performed based on morphological results. Growth of soybean seedlings was inhibited under flooding stress, ...

journal_title：Journal of proteomics

authors： Li X,Rehman SU,Yamaguchi H,Hitachi K,Tsuchida K,Yamaguchi T,Sunohara Y,Matsumoto H,Komatsu S

更新日期：2018-06-15 00:00:00

abstract：:Dendritic cells (DCs) can shape the immune system towards an inflammatory or tolerant state depending on the bacterial antigens and the environment they encounter. In this study we provide a proteomic catalogue of differentially expressed proteins between distinct DC maturation states, brought about by bacteria that d...

journal_title：Journal of proteomics

authors： Korkmaz AG,Popov T,Peisl L,Codrea MC,Nahnsen S,Steimle A,Velic A,Macek B,von Bergen M,Bernhardt J,Frick JS

更新日期：2018-05-30 00:00:00

abstract：:Many antibiotics are used to kill pathogenic Escherichia coli each year, resulting in an increase in the number of antibiotic-resistant strains. In this study, an integrated metabonomic-proteomic method was performed to systematically compare the profiles of metabolites and proteins with or without ciprofloxacin (CFLX...

journal_title：Journal of proteomics

authors： Li W,Zhang S,Wang X,Yu J,Li Z,Lin W,Lin X

更新日期：2018-05-15 00:00:00

abstract：:To seek a potential target for periodontal tissue regeneration, this study aimed to explore the role of Integrin alpha 5 (ITGA5) in human periodontal ligament stem cells (PDLSCs). Transwell assay, Cell Counting Kit 8 (CCK8) assay, cell cycle assay, alkaline phosphatase (ALP) activity, alizarin red staining, and wester...

journal_title：Journal of proteomics

authors： Wang H,Li J,Zhang X,Ning T,Ma D,Ge Y,Xu S,Hao Y,Wu B

更新日期：2018-05-15 00:00:00

abstract：:In continuity with the review dealing with differences by gender in non-sexual organs [1], this review collects data on the proteomes of the sexual organs as involved in human reproduction, under both physiological and pathological conditions. It also collects data on the tissue structures and biological fluids typica...

journal_title：Journal of proteomics

authors： Gianazza E,Miller I,Guerrini U,Palazzolo L,Parravicini C,Eberini I

更新日期：2018-04-30 00:00:00

abstract：:Lignocellulosic plant biomass is the most abundant carbon source in the planet, which makes it a potential substrate for biorefinery. It consists of polysaccharides and other molecules with applications in pharmaceutical, food and feed, cosmetics, paper and textile industries. The exploitation of these resources requi...

journal_title：Journal of proteomics

authors： García-Calvo L,Ullán RV,Fernández-Aguado M,García-Lino AM,Balaña-Fouce R,Barreiro C

更新日期：2018-04-15 00:00:00

abstract：:Plant-derived smoke plays a key role in seed germination and plant growth. To investigate the effect of plant-derived smoke on chickpea, a gel-free/label-free proteomic technique was used. Germination percentage, root/shoot length, and fresh biomass were increased in chickpea treated with 2000 ppm plant-derived smoke ...

journal_title：Journal of proteomics

authors： Rehman A,Rehman SU,Khatoon A,Qasim M,Itoh T,Iwasaki Y,Wang X,Sunohara Y,Matsumoto H,Komatsu S

更新日期：2018-03-30 00:00:00

abstract：:Jasmonate ZIM-domain (JAZ) proteins are key transcriptional repressors regulating various biological processes. Although many studies have studied JAZ proteins by genetic and biochemical analyses, little is known about JAZ7-associated global protein networks and how JAZ7 contributes to bacterial pathogen defense. In t...

journal_title：Journal of proteomics

authors： Zhang T,Meng L,Kong W,Yin Z,Wang Y,Schneider JD,Chen S

更新日期：2018-03-20 00:00:00

abstract：:Top-down proteomics (TDP) has great potential for high throughput proteoform characterization. With significant advances in mass spectrometry (MS) instrumentation permitting tandem MS of large intact proteins, a limitation to the widespread adoption of TDP still resides on front-end sample preparation protocols (e.g. ...

journal_title：Journal of proteomics

authors： Kachuk C,Doucette AA

更新日期：2018-03-20 00:00:00

abstract：:Structural mass spectrometry with its various techniques is a powerful tool for the structural elucidation of medically relevant protein assemblies. It delivers information on the composition, stoichiometries, interactions and topologies of these assemblies. Most importantly it can deal with heterogeneous mixtures and...

journal_title：Journal of proteomics

authors： Politis A,Schmidt C

更新日期：2018-03-20 00:00:00

abstract：:Lysine succinylation is a newly identified protein post-translational modification (PTM) of lysine residues. Increasing evidences demonstrate that this modification is prevalent in mitochondria and regulates many vital cellular processes, especially metabolism. Here, we determined the succinylome of the silkworm (Bomb...

journal_title：Journal of proteomics

authors： Chen J,Li F,Liu Y,Shen W,Du X,He L,Meng Z,Ma X,Wang Y

更新日期：2018-03-01 00:00:00

abstract：:No effective screening method is available for oral squamous cell carcinoma (OSCC) that is recognized to influence by environmental factors as well as human papillomavirus (HPV) and Epstein-Barr virus (EBV). Therefore, we sought to identify salivary biomarkers for screening of OSCC with or without HPV and/or EBV infec...

journal_title：Journal of proteomics

authors： Heawchaiyaphum C,Pientong C,Phusingha P,Vatanasapt P,Promthet S,Daduang J,Teeramatwanich W,Kongyingyoes B,Chuerduangphui J,Ekalaksananan T

更新日期：2018-02-20 00:00:00

abstract：:Numerous surveys have highlighted the natural co-occurrence of deoxynivalenol (DON) and zearalenone (ZEA) mycotoxins in food and feed. Nevertheless, data regarding cellular mechanisms involved in response to their individual and simultaneous exposures are lacking. In this study, in order to analyze how low mycotoxin d...

journal_title：Journal of proteomics

authors： Smith MC,Timmins-Schiffman E,Coton M,Coton E,Hymery N,Nunn BL,Madec S

更新日期：2018-02-20 00:00:00

abstract：:Molecular initiating events and downstream transcriptional/proteomic responses provide valuable information for adverse outcome pathways, which can be used predict the effects of chemicals on physiological systems. There has been a paucity of research that addresses sex-specific expression profiling in toxicology and ...

journal_title：Journal of proteomics

authors： Liang X,Feswick A,Simmons D,Martyniuk CJ

更新日期：2018-02-10 00:00:00

abstract：:Considering that proteins are usually engaged in complex and dynamic networks of interactions to exert their activity, a way to understand proteins' functions and the molecular mechanisms in which those proteins are involved, is by studying their interactome. In this sense, this tutorial presents a simple pipeline for...

journal_title：Journal of proteomics

authors： Anjo SI,Martins-Marques T,Pereira P,Girão H,Manadas B

更新日期：2018-01-16 00:00:00

abstract：:Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF-MS) is a rapid methodology for identification of bacteria that is increasingly used in diagnostic laboratories. This work aimed at evaluating the potential of MALDI-TOF-MS for identification of the main serotypes of Flavobacterium ...

journal_title：Journal of proteomics

authors： Fernández-Álvarez C,Torres-Corral Y,Santos Y

更新日期：2018-01-06 00:00:00

abstract：:Calcium (Ca2+) controls progression through the mammalian cell cycle by engaging a diverse range of molecular pathways. While the essential role of spatio-temporal Ca2+ signalling in the cell cycle is well established, the precise mechanisms by which it regulates cell cycle entry and progression through G1 are not par...

journal_title：Journal of proteomics

authors： Kwasnik A,von Kriegsheim A,Irving A,Pennington SR

更新日期：2018-01-06 00:00:00

abstract：:Many scorpion accidents occur in the Brazilian Amazonian region and are frequently caused by Tityus obscurus. Approximately 5% of the crude venom of this species is composed of short linear, non-disulfide-bridged peptides, which have not been intensively investigated. As a consequence, only a few of these peptides hav...

journal_title：Journal of proteomics

authors： Dias NB,de Souza BM,Cocchi FK,Chalkidis HM,Dorce VAC,Palma MS

更新日期：2018-01-06 00:00:00

abstract：:Drought stress, a major abiotic stress, commonly occurs in metal-contaminated environments and affects crop growth and yield. In this study, we performed the first integrated phenotypic, physiological, and proteomic analysis of Brachypodium distachyon L. seedling leaves under polyethylene glycol (PEG) mock osmotic str...

journal_title：Journal of proteomics

authors： Cheng ZW,Chen ZY,Yan X,Bian YW,Deng X,Yan YM

更新日期：2018-01-06 00:00:00

abstract：:Physical activity improves overall health and counteracts metabolic pathologies. Adipose tissue and bone are important key targets of exercise; the prevalence of diseases associated with suboptimal physical activity levels has increased in recent times as a result of lifestyle changes. Mesenchymal stem cells (MSCs) di...

journal_title：Journal of proteomics

authors： Dalle Carbonare L,Manfredi M,Caviglia G,Conte E,Robotti E,Marengo E,Cheri S,Zamboni F,Gabbiani D,Deiana M,Cecconi D,Schena F,Mottes M,Valenti MT

更新日期：2018-01-06 00:00:00

abstract：:The somatic embryogenesis in conifers represents a suitable model of plant regeneration system facilitating studies of fundamental aspects of an early development as well as in vitro micropropagation. The aim of our study was to deeper understand the somatic embryogenesis in the conifer tree Pinus nigra Arn. Comparati...

journal_title：Journal of proteomics

authors： Klubicová K,Uvácková L,Danchenko M,Nemecek P,Skultéty L,Salaj J,Salaj T

更新日期：2017-10-03 00:00:00

abstract：:Solanaceae is one of the major economically important families of higher plants and has played a central role in human nutrition since the dawn of human civilization. Therefore, researchers have always been interested in understanding the complex behavior of Solanaceae members to identify key transcripts, proteins or ...

journal_title：Journal of proteomics

authors： Ghatak A,Chaturvedi P,Paul P,Agrawal GK,Rakwal R,Kim ST,Weckwerth W,Gupta R

更新日期：2017-10-03 00:00:00

abstract：:Aldosterone (Aldo) could induce cardiac fibrosis, a hallmark of heart disease. Aldo direct effects on collagen production in cardiac fibroblasts remain controversial. Our aim is to characterize changes in the proteome of adult human cardiac fibroblasts treated with Aldo to identify new proteins altered that might be n...

journal_title：Journal of proteomics

authors： Martínez-Martínez E,Ibarrola J,Lachén-Montes M,Fernández-Celis A,Jaisser F,Santamaría E,Fernández-Irigoyen J,López-Andrés N

更新日期：2017-08-23 00:00:00

abstract：:Haemophilus parasuis, a symbiotic bacteria of upper respiratory tract of swine, is the etiological agent of Glässer's disease, which is characterized by fibrinous polyserositis. Emodin, exhibits antibacterial activity against H. parasuis, yet the action mode has not been fully understood. In present study, isobaric ta...

journal_title：Journal of proteomics

authors： Li L,Tian Y,Yu J,Song X,Jia R,Cui Q,Tong W,Zou Y,Li L,Yin L,Liang X,He C,Yue G,Ye G,Zhao L,Shi F,Lv C,Cao S,Yin Z

更新日期：2017-08-23 00:00:00

abstract：:Expanding the sequencing depth of the peptides with a statistically significant quantitative change derived from a biological stimulation is critical. Here we demonstrate that optimization of LC gradient and analytical column construction can reveal over 30,000 unique peptides and 23,000 phosphopeptides at high confid...

journal_title：Journal of proteomics

authors： Ahsan N,Belmont J,Chen Z,Clifton JG,Salomon AR

更新日期：2017-08-08 00:00:00

abstract：:Gluten proteins are major determinants of the bread making quality of wheat, but also of important wheat-related disorders, including coeliac disease (CD), and allergies. We carried out a proteomic study using the total grain proteins from two low-gliadin wheat lines, obtained by RNAi, and the untransformed wild type ...

journal_title：Journal of proteomics

authors： García-Molina MD,Muccilli V,Saletti R,Foti S,Masci S,Barro F

更新日期：2017-08-08 00:00:00

abstract：:Growth temperature is a critical factor that affects cultivation of Arthrospira platensis which is a type of cyanobacterium widely known as Spirulina that has significant commercial value. To investigate the molecular mechanism underlying the thermotolerance of Spirulina, differential protein expression profiling was ...

journal_title：Journal of proteomics

authors： Chang R,Lv B,Li B

更新日期：2017-08-08 00:00:00

abstract：:Chloroplast, the energy organelle unique to plant cells, is a dynamic entity which integrates an array of metabolic pathways and serves as first level for energy conversion for the entire ecological hierarchy. Increasing amount of sequence data and evolution of mass spectrometric approaches has opened up new avenues f...

journal_title：Journal of proteomics

authors： Lande NV,Subba P,Barua P,Gayen D,Keshava Prasad TS,Chakraborty S,Chakraborty N

更新日期：2017-08-08 00:00:00

abstract：:Nine distinct venom serine proteases (vSPs) of Gloydius intermedius were studied by transcriptomic, sub-proteomic and phylogenetic analyses. Their complete amino acid sequences were deduced after Expression Sequence Tag (EST) analyses followed by cDNA cloning and sequencing. These vSPs appear to be paralogs and contai...

journal_title：Journal of proteomics

authors： Yang ZM,Yu H,Liu ZZ,Pei JZ,Yang YE,Yan SX,Zhang C,Zhao WL,Wang ZZ,Wang YM,Tsai IH

更新日期：2017-07-05 00:00:00

abstract：:This work combines the advantages of volatile metabolites profiling as a young growing research field with a non-invasive sampling technique using earwax "a neglected body secretion" for detection and monitoring of biomarkers for diabetes mellitus (types 1 and 2). Earwax samples were collected from 26 diabetic patient...

journal_title：Journal of proteomics

authors： Shokry E,de Oliveira AE,Avelino MAG,de Deus MM,Filho NRA

更新日期：2017-04-21 00:00:00

abstract：:There is a wide range of pathological conditions proved to be associated with inflammation. The inflammatory process offers protection against harmful stimuli such as induced cell injury and tissues damage by means of specialized mediators and cells. Alarmins, also known as endogenous danger signals or damage-associat...

journal_title：Journal of proteomics

authors： Boteanu RM,Suica VI,Uyy E,Ivan L,Dima SO,Popescu I,Simionescu M,Antohe F

更新日期：2017-02-05 00:00:00

abstract：:The Aotus nancymaae species has been of great importance in researching the biology and pathogenesis of malaria, particularly for studying Plasmodium molecules for including them in effective vaccines against such microorganism. In spite of the forgoing, there has been no report to date describing the biology of paras...

journal_title：Journal of proteomics

authors： Moreno-Pérez DA,García-Valiente R,Ibarrola N,Muro A,Patarroyo MA

更新日期：2017-01-30 00:00:00

abstract：:Oligodendrocytes produce and maintain the myelin sheath of axons in the central nervous system. Because misassembled myelin sheaths have been associated with brain disorders such as multiple sclerosis and schizophrenia, recent advances have been made towards the description of the oligodendrocyte proteome. The identif...

journal_title：Journal of proteomics

authors： Tavares R,Wajnberg G,Scherer NM,Pauletti BA,Cassoli JS,Ferreira CG,Paes Leme AF,de Araujo-Souza PS,Martins-de-Souza D,Passetti F

更新日期：2017-01-16 00:00:00

abstract：BACKGROUND:Oral leukoplakia is the most common potentially malignant disorder in the oral cavity and can precede carcinoma. This study aimed to identify possible oral leukoplakia salivary biomarkers. METHODS:Unstimulated saliva was collected from participants and protein concentration was determined. Proteins were the...

journal_title：Journal of proteomics

authors： Camisasca DR,da Rós Gonçalves L,Soares MR,Sandim V,Nogueira FC,Garcia CH,Santana R,de Oliveira SP,Buexm LA,de Faria PA,Dias FL,Pereira DA,Zingali RB,Alves G,Lourenço SQ

更新日期：2017-01-16 00:00:00

abstract：:Dufour's gland is associated with the venom apparatuses of social wasps and bees. This location and its evolutionary adaptations indicate that it could be involved in the production of alarm pheromones in the social wasp Polybia paulista. To investigate this hypothesis, the volatile composition of this gland was analy...

journal_title：Journal of proteomics

authors： Esteves FG,Santos-Pinto JR,Saidemberg DM,Palma MS

更新日期：2017-01-16 00:00:00

abstract：:A large-scale proteomic approach was devised to advance the understanding of venom composition. Bothrops jararaca venom was fractionated by OFFGEL followed by chromatography, generating peptidic and proteic fractions. The latter was submitted to trypsin digestion. Both fractions were separately analyzed by reversed-ph...

journal_title：Journal of proteomics

authors： Nicolau CA,Carvalho PC,Junqueira-de-Azevedo IL,Teixeira-Ferreira A,Junqueira M,Perales J,Neves-Ferreira AG,Valente RH

更新日期：2017-01-16 00:00:00

abstract：:Toxoplasma gondii is a ubiquitous, obligate intracellular parasite capable of crossing the placental barrier and causing spontaneous abortion, preterm labor, or significant disease in the surviving neonate. To better understand molecular mechanisms underlying abnormal pregnancy outcomes caused by T. gondii, placental ...

journal_title：Journal of proteomics

authors： Jiao F,Zhang D,Jiang M,Mi J,Liu X,Zhang H,Hu Z,Xu X,Hu X

更新日期：2017-01-06 00:00:00

abstract：:Intrauterine growth restriction (IUGR) is an important cause of perinatal morbidity and mortality and contributes substantially to medically indicated preterm birth; preventing fetal death. Molecular profiling of the mothers' peripheral blood was desired to monitor the health conditions of the fetuses. To develop such...

journal_title：Journal of proteomics

authors： Wölter M,Röwer C,Koy C,Rath W,Pecks U,Glocker MO

更新日期：2016-10-21 00:00:00

abstract：UNLABELLED:Jellyfish sting has become a worldwide issue of critical concern to human health and safety in coastal areas in recent decades. Cyanea nozakii is one of the dominant blooming species and dangerous stingers in China. However, it remains unclear how many and what types of toxins are present in the venom. So, w...

journal_title：Journal of proteomics

authors： Li R,Yu H,Yue Y,Liu S,Xing R,Chen X,Li P

更新日期：2016-10-04 00:00:00